UTL_SMTP send mail wield problem????

we have ORACLE 10.2.0.4 with�Redhat AS�4.4 on DELL server.� Recently we are test "UTL_SMTP" on ORACLE PL/SQL program and tried to send MAIL to customers.
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The problem is this send MAIL program always one time work and second time not work (loop).� I don't think problem come from ORACLE bug or any ORACLE relate problem.� If I copy database and put on anyother server, it work correctly.
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Does anyone have suggestion?
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====== sample event happen� ===
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Connected to:
Oracle Database 10g Enterprise Edition Release 10.2.0.3.0 - Production With the Partitioning, OLAP and Data Mining options SQL> @mailbody
�31� .

SQL> /
Declare
*
ERROR at line 1:

ORA-29278: SMTP transient error: 421 Service not available
ORA-06512: at "SYS.UTL_SMTP", line 21
ORA-06512: at "SYS.UTL_SMTP", line 97
ORA-06512: at "SYS.UTL_SMTP", line 139
ORA-06512: at line 15

SQL> /
PL/SQL procedure successfully completed.
�
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SQL> /
Declare
*
ERROR at line 1:

ORA-29278: SMTP transient error: 421 Service not available
ORA-06512: at "SYS.UTL_SMTP", line 21
ORA-06512: at "SYS.UTL_SMTP", line 97
ORA-06512: at "SYS.UTL_SMTP", line 139
ORA-06512: at line 15


      

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