SQL> create or replace function f (v1 out number, v2 out number) return number
  2  is
  3  begin
  4    v1 := 1;
  5    v2 := 2;
  6    return 0;
  7  end;
  8  /

Function created.

SQL> declare
  2    l0 number;
  3    l1 number;
  4    l2 number;
  5  begin
  6    l0 := f (l1, l2);
  7    dbms_output.put_line ('l0='||l0||', l1='||l1||', l2='||l2);
  8  end;
  9  /
l0=0, l1=1, l2=2

PL/SQL procedure successfully completed.